Section iv when you are finished with this section, you will. Little is known about the routes of administration roa involved in nonmedical prescription opioid use among rural and urban drug users. It is a method of delivering the drug directly into the blood stream without having to pass the oral or alimentary mucous layer. The food and drug administration receives more than 100,000 reports of medication errors annually through its medwatch program. Chapter formulation development of parenteral products. Lisa burns manager, regulatory affairs 500 charles ewing blvd ewing, new jersey 08628 re.
A scheme of the different sites for parenteral drug administration is presented in figure 6. Australian and new zealand college of anaesthetists anzca. Medication administration considerations in hamsters and gerbils. The intrathecal route of administration should no longer be thought of as an exotic way of treating diseases of the nervous system. Routes of drug administration pharmacology 3571 with. Drug therapy pharmacotherapy is an important part of the medical field and relies on the science of pharmacology for continual advancement and on pharmacy for appropriate management. You must check for all six rights every time you administer any drug to any individual. Route of administration for illicit prescription opioids. Dosage form design may also be used modify the rate of absorption. When the patient takes a tablet or capsule, ensure that water is available to the patient for ease of swallowing the medication. The authors make no claims of the accuracy of the information contained herein. The intramuscular route is preferred to the subcutaneous route when larger volumes of a drug product are needed. Parenteral mode of drug administration that avoids the git. Administration each prefilled syringe of kynamro provides 200 mg of mipomersen sodium in a deliverable volume of 1 milliliter ml of solution and is intended for singleuse only.
Drugs applied to the skin are usually used for their local effects and thus are most commonly used to treat superficial skin disorders, such as psoriasis, eczema, skin infections viral, bacterial, and fungal, itching, and dry skin. Principles of pharmacology and ordering of drugsppt document free download as powerpoint presentation. Study 14 parenteral and nonparenteral methods of drug administration flashcards from chelsea a. Drug administration drugs msd manual consumer version. Parenteral drug administration their types, advantages.
A drug given parenterally is one given by a route other than the mouth topical dosage forms are considered separately. If volumes of 2 ml are required, an alternative route of. Routes of administration of a drug are determined by its physical and chemical properties, patient characteristics and the rapidity of response desired. Care should be taken to avoid needlestick injuries, which may transmit infections, e. Briskly compress the syringe plunger to deliver the medication. The fda is responsible for protecting and promoting public health through the control and supervision of food safety, tobacco products, dietary supplements, prescription.
This list is made up of brandname and generic prescription drugs approved by the u. Drug delivery characteristics and pharmacodynamic properties vary depending on the route of administration chosen for the drug. Parenteral administration of drugs is generally limited to subcutaneous, intramuscular, intraperitoneal, or intraosseous routes table. This article deals with the salient features, advantages and disadvantages of some of the alternative routes of drug administration transdermal, pulmonary and parenteral routes. Each time that you give a medication, you also need to remember to do the three checks.
Use of aseptic technique very very important intravenous iv injections fast action due to avoidance of gi absorption intradermal injected into the dermis. The purpose of this study was to describe ruralurban differences in roa for nonmedical. Absorption after oral administration can be quite variable. A medication also referred to as medicine, pharmaceutical drug, or simply drug is a drug used to diagnose, cure, treat, or prevent disease. The three main parenteral routes of drug administration are iv, im, and sc, and in all cases administration is usually via a hollow needle. Food and drug administration 10903 new hampshire avenue silver spring, md 20993 1888infofda 18884636332 contact fda. The various routes of administrations are classified into following categories. The parenteral route of drug administration is now considered the most effective route as it provides a rapid onset of action, a good bioavailability of the drugs and a reliable option for drug. The oral route of administration is the safest, most economical and the most convenient way of giving medicines. Injectable preparations are usually sterile solutions or suspensions of drug in water. To ensure safe drug administration, nurses are encouraged to follow the five rights rs.
National drug list drug list four tier drug plan your prescription benefit comes with a drug list, which is also called a formulary. Principles of drug administration flashcards quizlet. Patient condition be alert to changes that can affect drug therapy. The parenteral drug association pda is the leading global facilitator of science, technology and regulatory information. Principles of pharmacology and ordering of drugsppt. Food and drug administration 9200 corporate boulevard apr 2 7 2005 rockville md 20850 ms. Quizlet flashcards, activities and games help you improve your grades. Drug is applied to the skin or mucous membrane at various sites for local action. The food and drug administration fda is articulating its enforcement strategy in order to. Read the label of the drug carefully before administering a drug to the patient. Chapter 3 drug administration study guide by mhdoggett includes 55 questions covering vocabulary, terms and more. With current implantable technology, access to the lumbar subarachnoid space is clinically acceptable and carries a low risk of infection. Camille harris, in manual of exotic pet practice, 2009. Route of administration an overview sciencedirect topics.
Well email you at these times to remind you to study. Strict aseptic precautions should be taken while giving injections. Drug administration definition of drug administration by. Nonmedical prescription opioid use has emerged as a major public health concern in recent years, particularly in rural appalachia. Drugs are usually injected into the muscle of the upper arm, thigh, or buttock. Introduction drug administration is very important and can be a dangerous duty given correctly restore patient to health given incorrectly patients condition can worsen medical assistant must understand principles of pharmacology understand fundamentals of drug administration routes dosage calculations. Parenteral preparations circumvent the intestinal tract and, therefore, are not subject to pharmacodynamic properties. Summary food and drug administration advisory committees. The drug administration schedule can sometimes be flexible in order to accommodate the clients activities for the day or preferences. Aerosols localtopical route of drug administration in this route the drug is applied on the skin. Any medical information need spontaneous update and we will do our best to be in correct way. Its the nurses responsibility to be aware of tests or procedures that are taking place that may affect the medication administration. A route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body. Box 221 five rights of drug administration right drug right amount right patient right time right route the five rights are as follows.
Drug administration guidelines for calendar year 2010 cms drug administration instructions. Routes of drug administration oral po oral administration will be covered in more detail in subsequent chapters. The route of administration of a drug in vivo can be a means of increasing the delivery of the drug to a given organ to optimize the active concentration at the therapeutic target. A route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body routes of administration are generally classified by the location at which the substance is applied. Because the muscles lie below the skin and fatty tissues, a longer needle is used. If volumes of 2 ml are required, an alternative route of administration should be sought. Route of administration for rodents are guided by temperament, size, and restraint methods. Oral administration is a safe and convenient method of drug administration if a few simple rules are followed. Introduction the safe administration of drugs in anaesthesia encompasses the timely administration of medication to patients, the prevention of drug administration errors, and measures to reduce the opportunity to misdirect drugs.
Side effects can include those that occur when the drug is deposited directly in the lungs such as cough, wheezing, shortness of breath, and lung irritation, spread of the drug into the environment possibly affecting people other than the one taking the drug, and contamination of the device used for nebulization particularly when the. Sc administrat ion of drugs consists in injecting them under the skin into the adipose layer. The aim of this study, carried out in a district general hospital, was to identify any common themes that underlie the occurrence and reporting of drug administration errors. This applies to any medication irrespective of the route of administration. Section iv when you are finished with this section, you. Inhalation is a very old method of drug delivery, and in the 20th century it became a mainstay of respiratory care, known as aerosol therapy. As a minimum, the name, concentration where dilution has occurred or different concentrations are available and expiry date of the drug must be checked.
Introduction drug administration is very important and can be a dangerous duty given correctly restore patient to health given incorrectly patients condition can worsen medical assistant must understand principles of pharmacology understand fundamentals of drug administration. Gently shake the elixir preparation to ensure the contents are thoroughly mixed. The food and drug administration fda or usfda is a federal agency of the united states department of health and human services, one of the united states federal executive departments. Stop ensure that you have made the check of the five rights before you administer any drug to your patient. Systemic route a enteral route b parenteral route 1. Parenteral and nonparenteral methods of drug administration. Guidelines for the safe management and use of medications in anaesthesia 1. Unlike taking medications orally or rectally, introducing a drug into the body by parenteral administration.
In this administration the drug is administered in the gaseous form. Using a sterile syringe, withdraw the desired amount of elixir solution. Use of inhaled epinephrine for relief of asthma was reported as early as 1929, in england. Routes of administration and dosage forms pharmacology. Routes can also be classified based on where the target of action is. Drugdrug or fooddrug interactions that affect the metabolism and excretion of drug in the body. A route of administration in pharmacy is the path by which a drug is taken into the body. Ten rights of medication administration palm beach state. This route of administration is possible if the drug is in liquid dosage form. Guidelines for drug administration kee, hayes, and mccuistion. Introduction medication is transferred into the bodys tissues in one of three ways. It can also effectively reduce the sideeffects to a drug in vivo. Use full set of drug administration cpt codes, including those codes referencing concepts of initial, concurrent, and sequential, to. Lewis senior regulatory affairs specialist alaris medical systems, incorporated 1022 1 wateridge circle san diego, california 921212733 re.